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| Hegedüs,R.M.; Michima,L.E.S.; Souza,V.R.C.; Dutra,G.H.P.; Fernandes,W.R.; Coelho,C.S.. |
| Avaliaram-se os efeitos da furosemida sobre o lavado traqueal de eqüinos portadores de hemorragia pulmonar induzida pelo exercício (HPIE). Nove animais foram distribuídos em três grupos experimentais: grupo-controle, formado por três eqüinos hígidos e não portadores da doença; grupo 1, com três eqüinos portadores e não submetidos a tratamento; e grupo 2, com três eqüinos portadores da doença e tratados com furosemida na dose de 1mg/kg, quatro horas antes da atividade atlética. As amostras do lavado traqueal foram obtidas duas horas após o exercício físico e sua avaliação demonstrou que o uso do medicamento reduziu a severidade da HPIE, refletida pela redução no número relativo de hemossiderófagos (de 7,8% no grupo 1 para 4,2% no grupo 2) e no número de... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Equine; Pulmonary hemorrhage; Tracheal wash; Furosemide. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000200040 |
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| Levi,T.M.; Rocha,M.S.; Almeida,D.N.; Martins,R.T.C.; Silva,M.G.C.; Santana,N.C.P.; Sanjuan,I.T.; Cruz,C.M.S.. |
| Acute kidney injury (AKI) is common in critically ill patients. Diuretics are used without any evidence demonstrating a beneficial effect on renal function. The objective of the present study is to determine the incidence of AKI in an intensive care unit (ICU) and if there is an association between the use of furosemide and the development of AKI. The study involved a hospital cohort in which 344 patients were consecutively enrolled from January 2010 to January 2011. A total of 132 patients (75 females and 57 males, average age 64 years) remained for analysis. Most exclusions were related to ICU discharge in the first 24 h. Laboratory, sociodemographic and clinical data were collected until the development of AKI, medical discharge or patient death. The... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Acute renal failure; Critically ill patients; Furosemide; Septic shock. |
| Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000900006 |
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| Rowland,N.E.. |
| Several studies of the quantitative relationship between sodium need and sodium intake in rats are reviewed. Using acute diuretic treatment 24 h beforehand, intake matches need fairly accurately when intake is spread out in time by using a hypotonic solution of NaCl. In contrast, using a hypertonic solution, intake is typically double the need. Using the same diuretic treatment, although the natriuresis occurs within ~1 h, the appetite appears only slowly over 24 h. Increased plasma levels of aldosterone parallel the increased intake; however, treatment with metyrapone blocks the rise in aldosterone but has no effect on appetite. Satiation of sodium appetite was studied in rats using sodium loss induced by chronic diuretic treatment and daily salt... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Furosemide; Sodium depletion; Progressive ratio; Aldosterone; Satiation. |
| Ano: 2007 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000500016 |
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| Caruso-Neves,C.; Rangel,L.B.A.; Lara,L.S.; Lopes,A.G.. |
| For several years it was believed that angiotensin II (Ang II) alone mediated the effects of the renin-angiotensin system. However, it has been observed that other peptides of this system, such as angiotensin-(1-7) (Ang-(1-7)), present biological activity. The effect of Ang II and Ang-(1-7) on renal sodium excretion has been associated, at least in part, with modulation of proximal tubule sodium reabsorption. In the present review, we discuss the evidence for the involvement of Na+-ATPase, called the second sodium pump, as a target for the actions of these compounds in the regulation of proximal tubule sodium reabsorption. |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Na+-ATPase; Angiotensin II; Angiotensin-(1-7); Furosemide; Proximal tubule. |
| Ano: 2001 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000800015 |
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| Santos,Carolina Alves dos; Mazzola,Priscila Gava; Polacwiecz,Bronislaw; Knirsch,Marcos Camargo; Cholewa,Olívia; Penna,Thereza Christina Vessoni. |
| Parenteral solutions (PS) are one of the most commonly used drug delivery vehicles. Interactions among the drug, components in the drug's formulation, and the PS can result in the formation of inactive complexes that limit efficacy or increase side effects. The aim of this work was to evaluate possible interactions between the drugs and PS, assess drug stability and to identify degradation products after 20 h at room temperature. Furosemide (FSM) and Aminophylline (APN) were added to PS containing either 20% mannitol or 0.9% NaCl at pH 6.5-7.5 and 10-11. Their behavior was studied individually and as an admixture, after 1 h oxidation with H2O2, using a spectrophotometer and HPLC. Individually, FSM and APN added to 20% mannitol and 0.9% NaCl solutions had... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Parenteral solutions; Spectrophotometer; High Performance Liquid Chromatography; Furosemide; Aminophylline. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000100011 |
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